(Co)Development

PySEQM

PYSEQM is a Semi-Empirical Quantum Mechanics package implemented in PyTorch. It provides built-in interfaces for machine learning and efficient molecular dynamic engines with GPU supported.

Official repository: https://github.com/lanl/PYSEQM

libmbd

Libmbd implements the many-body dispersion (MBD) method in several programming languages and frameworks. Libmbd is included in FHI-aims, Quantum Espresso, DFTB+, and ESL Bundle.

Official repository: https://github.com/libmbd/libmbd

Hotbit

Hotbit is an ASE density-functional tight-binding calculator that aims to provide an open-source DFTB code, a handy companion for DFT, a compact and accessible code for everyone to inspect and modify, an intuitive user interface (ideal for learning and teaching realistic electronic structure simulations), DFTB parametrization suite including interface to libxc.

Official repository: https://github.com/pekkosk/hotbit

DFTB+

DFTB+ is a software package for carrying out fast quantum mechanical atomistic calculations based on the Density Functional Tight Binding method.

Official repository: https://github.com/dftbplus/dftbplus

Regular Usage

FHI-aims

FHI-aims is an efficient, accurate all-electron, full-potential electronic structure code package for computational molecular and materials science (non-periodic and periodic systems). The code supports DFT (semilocal and hybrid) and many-body perturbation theory. FHI-aims is particularly efficient for molecular systems and nanostructures, while maintaining high numerical accuracy for all production tasks. Production calculations handle up to several thousand atoms and can efficiently use (ten) thousands of cores.

Webpage: https://aimsclub.fhi-berlin.mpg.de

GROMACS

GROMACS is a versatile package to perform molecular dynamics, i.e. simulate the Newtonian equations of motion for systems with hundreds to millions of particles. It is primarily designed for biochemical molecules like proteins, lipids and nucleic acids that have a lot of complicated bonded interactions, but since GROMACS is extremely fast at calculating the nonbonded interactions (that usually dominate simulations) many groups are also using it for research on non-biological systems, e.g. polymers.

Webpage: https://www.gromacs.org/

TeraChem

TeraChem is a general purpose GPU-accelerated electronic structure package designed for Nvidia CUDA-enabled GPU architectures primarily developed by the Martínez group and collaborators and owned by PetaChem, LLC.

See https://mtzweb.stanford.edu/software

Atomic Simulation Environment

ASE is a set of tools and Python modules for setting up, manipulating, running, visualizing and analyzing atomistic simulations. Webpage: https://wiki.fysik.dtu.dk/ase

Official repository: https://gitlab.com/ase/ase

© 2026 | Martin Stöhr